Cytology, Genetics and Cytogenetics (PDF)

Cytology, Genetics and Cytogenetics
Author Name: Prabhat & Nitu Nisha
Edition: First Edition
Release at: 25 May 2026
Pages: 340
Language: Hindi
File Size: 23.6 MB
File Type: PDF
Prize: 249 INR

Cytology, Genetics and Cytogenetics written by Prabhat & Nitu Nisha is a great book for Cell Biology and Genetics, book available in PDF download. The Book Design specially for Degree Students who do master in Botany, Microbiology, Zoology and Genetics subjects.

The fields of genetics and molecular biology are continuously and rapidly evolving, forming the cornerstone of modern life sciences. This book is meticulously crafted for students, researchers, and science enthusiasts who wish to build a profound understanding of genetics—from its fundamental principles to its advanced molecular and applied aspects.

To present the complexity of the subject in a simple, logical, and engaging manner, the text has been systematically organized into four distinct units:

  • Unit-I: Lays the foundation by exploring chromosome structure, specialized types (such as Polytene and Lampbrush chromosomes), and structural and numerical aberrations. It also sheds light on karyotype analysis, allopolyploids, and the fascinating evolutionary history of major crop plants.
  • Unit-II: Focuses on the genetic mechanics of prokaryotes and eukaryotes. It provides a clear breakdown of the bacteriophage genome, bacterial recombination (conjugation, transduction, transformation), gene structure, RNA splicing, and the intricate regulation of gene expression.
  • Unit-III: Delves deep into the molecular level, covering recombination, chromosome mapping, and the molecular basis of spontaneous and induced mutations. It additionally addresses critical contemporary topics, including transposable elements, DNA damage and repair mechanisms, and the cellular initiation of cancer involving proto-oncogenes.
  • Unit-IV: Dedicated to applied cytogenetics, molecular mapping, and plant breeding. It navigates through the complexities of aneuploidy, the C-value paradox, in situ hybridization (ISH), and whole genome transfer in vital crops like Triticum (wheat), Arachis (peanut), and Brassica. The unit concludes with the foundational concepts and practical exploitation of inbreeding and heterosis (hybrid vigor).
  • The language and presentation of this book are specifically designed to make intricate scientific concepts highly accessible. It serves not only as an essential textbook for undergraduate and postgraduate academic courses but also as a highly valuable resource for candidates preparing for competitive scientific examinations.


UNIT I

  • Chromosome Structure & Packing of DNA
  • Molecular Organization of the Centromere & Telomere
  • Nucleolus & Ribosomal RNA Gene
  • Euchromatin
  • Karyotype Analysis & Evolution
  • Polytene Chromosomes
  • Lampbrush Chromosomes
  • B-Chromosomes
  • Sex Chromosomes
  • Structural Aberrations
  • Numerical Aberrations
  • Allopolyploids: Types, Genome Constitution, & Analysis
  • Evolution of Major Crop Plants

UNIT II

  • Genetics of Prokaryotes & Eukaryotes Organelles: Mapping the Bacteriophage Genome
  • Genetic Recombination in Phage
  • Genetic Transformation
  • Conjugation & Transduction in Bacteria
  • Cytoplasmic Male Sterility
  • Gene Structure and Expression: Genetic Fine Structure
  • Cis-Trans Test
  • Introns & Their Significance
  • RNA Splicing
  • Regulation of Gene Expression in Prokaryotes & Eukaryotes

UNIT III

  • Recombination, Independent Assortment & Crossing Over
  • Role of RecA & RecBCD Enzyme in Recombination
  • Site-Specific Recombination
  • Chromosome Mapping
  • Linkage Groups
  • Genetic Markers
  • Correlation of Genetic & Physical Maps
  • Mutations: Spontaneous and Induced Mutations
  • Molecular Basis of Gene Mutations
  • Transposable Elements in Prokaryotes & Eukaryotes
  • Mutation: Molecular Basis of Transposons
  • Site-Directed Mutagenesis
  • DNA Damage & Repair Mechanisms
  • Inherited Human Disease & Defects in DNA Repair
  • Initiation of Cancer at the Cellular Level
  • Proto-Oncogenes & Oncogenes

UNIT IV

  • Effect of Aneuploidy on Phenotype in Plants
  • Transmission of Monosomics & Trisomics & Their Use in Chromosome Mapping of Diploid & Polyploid Species
  • Breeding Behavior
  • Complex Translocation Heterozygotes
  • Robertsonian Translocation
  • B-A Translocation
  • Molecular Cytogenetics: Nuclear DNA Content
  • C-Value Paradox
  • Cot Curve & Its Significance
  • Restriction Mapping
  • In Situ Hybridization (ISH)
  • Physical Mapping of Genes on Chromosomes
  • Micro-Cloning
  • Transfer of Whole
  • Whole Genome Transfer in Triticum: The Tale of Allohexaploidy
  • Whole Genome Transfer in Arachis (Peanut)
  • Whole Genome Transfer in Brassica
  • Method for Detecting Alien Chromatin
  • Production, Characterization & Utility of Alien Genetics
  • Basis of Inbreeding & Heterosis
  • Exploitation of Hybrid Vigor
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